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LISA Technique — RACP Paediatrics MCQ

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HardNeonatologyLISA TechniqueRACP Paediatrics

A preterm infant at 24 weeks gestation is being given surfactant. What is the preferred method of surfactant administration in a spontaneously breathing preterm infant on CPAP?

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Correct answer: B — LISA (Less Invasive Surfactant Administration) via thin catheter while on CPAP

LISA (Less Invasive Surfactant Administration) involves administering surfactant via a thin catheter placed in the trachea while the infant remains on CPAP and breathes spontaneously. This avoids the need for intubation and mechanical ventilation. Multiple RCTs show reduced BPD and death compared to INSURE.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Surfactant Administration