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Caffeine Dosing — RACP Paediatrics MCQ

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ModerateNeonatologyCaffeine DosingRACP Paediatrics

A premature infant receives caffeine citrate for apnoea. What is the standard loading dose?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D20 mg/kg caffeine citrate (equivalent to 10 mg/kg caffeine base)

Caffeine citrate loading dose: 20 mg/kg caffeine citrate (= 10 mg/kg caffeine base) IV or oral. Maintenance dose: 5-10 mg/kg/day caffeine citrate. Therapeutic levels are rarely needed. The CAP trial demonstrated improved survival without neurodevelopmental disability.

Reference: AMH Children's Dosing Companion – 2024 – Caffeine Citrate