Initial FiO2 Term Resuscitation — RACP Paediatrics MCQ
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Correct answer: D — 0.21 (room air)
Current neonatal resuscitation guidelines recommend starting with room air (FiO2 0.21) for term neonates and titrating oxygen based on pulse oximetry to target preductal SpO2 goals. Starting with 100% oxygen is associated with increased oxidative stress and delayed time to first breath.
Reference: Australian Resuscitation Council – 2025 – Neonatal Resuscitation Guidelines