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Hashimoto Thyroiditis — RACP Paediatrics MCQ

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EasyEndocrinologyHashimoto ThyroiditisRACP Paediatrics

A 10-year-old girl presents with fatigue, weight gain, constipation, and dry skin. She has a firm, non-tender goitre. TSH is 45 mU/L and free T4 is low. Anti-TPO antibodies are strongly positive. What is the diagnosis?

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Correct answer: E — Hashimoto thyroiditis

Hashimoto thyroiditis (chronic lymphocytic thyroiditis) is the most common cause of acquired hypothyroidism in children. Anti-TPO and anti-thyroglobulin antibodies are positive. Treatment is levothyroxine replacement. TSH monitoring guides dose adjustment. The goitre may fluctuate in size.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Hypothyroidism