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GAS and APSGN — RACP Paediatrics MCQ

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EasyInfectious DiseaseGAS and APSGNRACP Paediatrics

A 10-year-old Aboriginal child in a remote community presents with haematuria and oedema 2 weeks after a skin sore. Anti-streptolysin O titre is elevated. C3 is low. What is the causative organism for the preceding skin infection most commonly associated with APSGN in Aboriginal communities?

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Correct answer: E — Group A Streptococcus (GAS)

In Aboriginal and Torres Strait Islander communities, GAS skin infections (impetigo/pyoderma) are the most common cause of APSGN. Nephritogenic GAS strains cause glomerulonephritis. APSGN remains a significant health problem in remote Australian communities.

Reference: NHMRC – 2024 – Management of GAS Disease in Aboriginal Communities