skip to main content

Landau-Kleffner Syndrome — RACP Paediatrics MCQ

Instant feedback + full explanation. One question, done properly.

HardNeurology & DevelopmentLandau-Kleffner SyndromeRACP Paediatrics

A 9-year-old previously normal child develops progressive language regression with an epileptiform EEG showing continuous spike-wave during slow-wave sleep (CSWS). Hearing is normal. What is the diagnosis?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Landau-Kleffner syndrome

Landau-Kleffner syndrome is an acquired epileptic aphasia presenting with language regression in a previously normal child, associated with epileptiform activity during slow-wave sleep. Seizures may or may not be present. Treatment includes corticosteroids, benzodiazepines, and speech therapy. Prognosis for language recovery is variable.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Epileptic Encephalopathies