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Childhood Absence Epilepsy Treatment — RACP Paediatrics MCQ

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ModerateNeurology & DevelopmentChildhood Absence Epilepsy TreatmentRACP Paediatrics

An 8-year-old boy presents with absence seizures occurring 10-20 times per day. EEG shows 3 Hz generalised spike-and-wave discharges. What is the first-line anti-seizure medication?

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Correct answer: E — Ethosuximide or sodium valproate

Childhood absence epilepsy: ethosuximide is first-line if absence seizures only (no GTCs). Sodium valproate is an alternative and is preferred if GTCs also occur. Carbamazepine and phenytoin can worsen absence seizures. Prognosis is generally good with remission by adolescence.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Epilepsy