skip to main content

Infantile Spasms Treatment — RACP Paediatrics MCQ

Instant feedback + full explanation. One question, done properly.

ModerateNeurology & DevelopmentInfantile Spasms TreatmentRACP Paediatrics

A 6-month-old presents with clusters of sudden flexor spasms, each lasting 1-2 seconds, occurring upon waking. EEG shows hypsarrhythmia. What is the recommended first-line treatment in Australia?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Prednisolone or ACTH

Infantile spasms (West syndrome): prednisolone (or ACTH) is the first-line treatment. Vigabatrin is first-line if TSC is the underlying cause. Rapid initiation of treatment is critical to optimise developmental outcomes. MRI brain should be performed to identify underlying structural causes.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Infantile Spasms