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PBB in High-Risk Children — RACP Paediatrics MCQ

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ModerateRespiratoryPBB in High-Risk ChildrenRACP Paediatrics

An 18-month-old Aboriginal child has a chronic moist cough for 6 weeks. He has had 3 previous episodes of acute lower respiratory tract infection. Flexible bronchoscopy with BAL shows neutrophilic inflammation and cultures grow Haemophilus influenzae. HRCT is normal. What is the recommended antibiotic duration?

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Correct answer: C4 weeks minimum

In children at high risk of bronchiectasis (including Aboriginal and Torres Strait Islander children with recurrent LRTI), antibiotic courses for PBB should be for a minimum of 4 weeks. Shorter courses are associated with early relapse and risk of bronchiectasis development.

Reference: Thoracic Society of Australia and New Zealand – 2024 – Position Statement on PBB