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ICS Growth Effects — RACP Paediatrics MCQ

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ModerateRespiratoryICS Growth EffectsRACP Paediatrics

A 16-year-old boy with severe asthma is on high-dose ICS/LABA. Annual height measurements show a growth velocity of 3 cm/year (expected >5 cm/year). What is the most likely cause?

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Correct answer: E — Systemic effect of high-dose inhaled corticosteroids

High-dose ICS can cause systemic side effects including adrenal suppression and reduced growth velocity, particularly with fluticasone. Growth should be monitored at least annually. The lowest effective ICS dose should be used.

Reference: National Asthma Council Australia – 2024 – Australian Asthma Handbook