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Neuroblastoma — RACP Paediatrics MCQ

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ModerateHaematology & OncologyNeuroblastomaRACP Paediatrics

A 3-year-old girl presents with a painless abdominal mass. Examination reveals a firm, irregular mass crossing the midline. Urine catecholamines (VMA and HVA) are elevated. Calcification is seen on abdominal X-ray. What is the most likely diagnosis?

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Correct answer: E — Neuroblastoma

Neuroblastoma: firm irregular mass that crosses the midline, elevated urine catecholamines, calcification on imaging. Most common extracranial solid tumour in children. Arises from sympathetic neural crest tissue.

Reference: ANZCHOG – 2024 – Treatment Guidelines: Neuroblastoma