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Haemophilia A — RACP Paediatrics MCQ

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ModerateHaematology & OncologyHaemophilia ARACP Paediatrics

A 12-year-old boy with known haemophilia A presents with a swollen, warm, painful right knee after a minor fall. His baseline factor VIII level is <1%. What is the most appropriate acute management?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Factor VIII replacement to achieve 40-50% levels, plus RICE

Acute haemarthrosis in severe haemophilia A requires prompt factor VIII replacement aiming for 40-50% trough levels. RICE (rest, ice, compression, elevation) and analgesia (avoid NSAIDs/aspirin) are adjuncts.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Haemophilia