Duodenal Atresia — RACP Paediatrics MCQ

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EasyNeonatologyDuodenal AtresiaRACP Paediatrics

A term neonate presents with bilious vomiting on day 1 of life. Abdominal X-ray shows a 'double bubble' sign with no distal gas. The infant has trisomy 21. What is the diagnosis?

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Correct answer: B — Duodenal atresia

Double bubble sign with no distal gas = complete duodenal obstruction, most likely duodenal atresia. Strong association with trisomy 21. Treatment is surgical (duodenoduodenostomy).

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Neonatal Intestinal Obstruction