Orbital Rhabdomyosarcoma — RACP Paediatrics MCQ

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HardHaematology & OncologyOrbital RhabdomyosarcomaRACP Paediatrics

A 14-month-old has rapidly enlarging orbital mass with proptosis. Biopsy shows desmin-positive small round blue cells. Diagnosis?

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Correct answer: E — Orbital rhabdomyosarcoma (embryonal)

Orbital rhabdomyosarcoma (embryonal): most common orbital malignancy in children. Desmin/myogenin positive.

Reference: ANZCHOG – 2024 – Treatment Guidelines: Rhabdomyosarcoma