Von Willebrand Disease — RACP Paediatrics MCQ

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ModerateHaematology & OncologyVon Willebrand DiseaseRACP Paediatrics

A 5-year-old has recurrent nosebleeds. FBC normal. APTT/PT normal. PFA-100 prolonged. Diagnosis?

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Correct answer: D — Von Willebrand disease

Normal FBC, normal coag, prolonged PFA-100 with mucocutaneous bleeding = VWD (most common inherited bleeding disorder).

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Bleeding Disorders