Cushing Syndrome — RACP Paediatrics MCQ

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HardEndocrinologyCushing SyndromeRACP Paediatrics

A 7-year-old has central obesity, purple striae, moon facies, hypertension. Elevated 24h urinary cortisol. Next best investigation?

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Correct answer: E — Overnight dexamethasone suppression test and ACTH level

After confirming hypercortisolism, determine if ACTH-dependent or independent.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Cushing Syndrome