Peripheral Precocious Puberty — RACP Paediatrics MCQ

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HardEndocrinologyPeripheral Precocious PubertyRACP Paediatrics

A 6-year-old has tall stature, breast development, growth velocity 12 cm/yr. LH suppressed on GnRH stim. Oestradiol elevated. Cause?

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Correct answer: E — Ovarian cyst or tumour (peripheral precocious puberty)

Peripheral precocious puberty: elevated sex steroids with suppressed gonadotrophins. Ovarian pathology most common in girls.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Precocious Puberty