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Acute Severe Ulcerative Colitis — RACP Paediatrics MCQ

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HardGastroenterologyAcute Severe Ulcerative ColitisRACP Paediatrics

An 8-year-old with UC presents with acute severe flare: bloody diarrhoea 8 times/day, CRP 85, albumin 22. On mesalazine. Most appropriate induction therapy?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — IV methylprednisolone

Acute severe UC (PUCAI score ≥65) requires IV corticosteroids. If no response in 3-5 days, rescue therapy with infliximab or colectomy is considered.

Reference: AUSPGHAN – 2024 – Position Statement on Paediatric IBD