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Non-IgE Mediated CMPA — RACP Paediatrics MCQ

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ModerateGastroenterologyNon-IgE Mediated CMPARACP Paediatrics

A 4-month-old formula-fed infant has severe eczema and blood-streaked stools. Specific IgE to cow's milk negative. SPT negative. What type of allergy?

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Correct answer: C — Non-IgE mediated cow's milk allergy

Delayed-onset symptoms with negative IgE and SPT is consistent with non-IgE mediated cow's milk allergy. Diagnosis is by elimination and rechallenge.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Non-IgE Mediated Food Allergy