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Cystic Fibrosis Exacerbation — RACP Paediatrics MCQ

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HardRespiratoryCystic Fibrosis ExacerbationRACP Paediatrics

A 12-year-old boy with known cystic fibrosis and chronic Pseudomonas colonisation develops an acute exacerbation with increased cough, purulent sputum, and a 5% fall in FEV1. What is the most appropriate treatment?

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Correct answer: E — IV anti-pseudomonal antibiotics (two agents) for 14 days

An acute pulmonary exacerbation in a CF patient with chronic Pseudomonas requires IV anti-pseudomonal therapy with two agents for 10-14 days.

Reference: Australian Cystic Fibrosis Guidelines – 2024 – Management of Pulmonary Exacerbations