Cellulitis — RACP Paediatrics MCQ

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EasyDermatologyCellulitisRACP Paediatrics

A 10-year-old girl presents with a rapidly spreading, tender, well-demarcated area of erythema, warmth, and swelling on her left leg. She has fever and leucocytosis. What is the most appropriate antibiotic?

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Correct answer: A — Oral flucloxacillin

Cellulitis in an otherwise well child without risk factors for MRSA is treated with oral flucloxacillin (or cefalexin) to cover Staphylococcus aureus and Streptococcus pyogenes. IV antibiotics are reserved for systemically unwell children, facial cellulitis, or failure of oral therapy. In areas with high community MRSA prevalence, trimethoprim-sulfamethoxazole or clindamycin may be added.

Reference: Therapeutic Guidelines – 2024 – Antibiotic: Skin and Soft Tissue Infections