Neonatal Resuscitation — RACP Paediatrics MCQ

Instant feedback + full explanation. One question, done properly.

ModerateNeonatologyNeonatal ResuscitationRACP Paediatrics

A preterm infant of 26 weeks gestation is born and requires resuscitation. During the initial steps of neonatal resuscitation, what initial FiO2 should be used for a preterm infant <28 weeks?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — 0.30

Australian Resuscitation Council and ILCOR guidelines recommend starting resuscitation of preterm infants <28 weeks gestation with an initial FiO2 of 0.21–0.30 (21–30%), titrated using pulse oximetry. Starting with 100% oxygen in preterm infants is associated with increased oxidative stress and adverse outcomes. For term infants, room air (0.21) is recommended as the starting FiO2.

Reference: Australian Resuscitation Council – 2025 – Neonatal Resuscitation Guidelines