Hodgkin Lymphoma — RACP Paediatrics MCQ

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ModerateHaematology & OncologyHodgkin LymphomaRACP Paediatrics

A 12-year-old boy presents with a rapidly enlarging painless cervical lymph node mass. Biopsy shows Reed-Sternberg cells in a background of mixed inflammatory cells. PET-CT shows involvement above and below the diaphragm. What is the staging?

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Correct answer: A — Stage III

Hodgkin lymphoma is staged using the Ann Arbor classification. Stage III indicates lymph node involvement on both sides of the diaphragm. Stage I = single lymph node region, Stage II = two or more regions on the same side of the diaphragm, Stage IV = disseminated extranodal disease. The presence of B symptoms (fever, weight loss >10%, night sweats) is denoted by suffix B.

Reference: ANZCHOG – 2024 – Treatment Guidelines: Hodgkin Lymphoma in Children