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Henoch-Schönlein Purpura Nephritis — RACP Paediatrics MCQ

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ModerateNephrologyHenoch-Schönlein Purpura NephritisRACP Paediatrics

A 5-year-old boy presents with Henoch-Schönlein purpura. He develops nephritic-range proteinuria and haematuria 2 weeks after the initial rash. His renal function is normal. What percentage of children with HSP develop renal involvement?

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Correct answer: B — 20–50%

Approximately 20–50% of children with HSP develop renal involvement (HSP nephritis), usually within the first 1–3 months. Risk factors include age >7 years and persistent purpura. Most cases are mild (microscopic haematuria +/- mild proteinuria) and resolve. Severe cases with nephrotic-range proteinuria or renal impairment may require biopsy and immunosuppressive treatment.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Henoch-Schönlein Purpura