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Hand Foot and Mouth Disease — RACP Paediatrics MCQ

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EasyInfectious DiseaseHand Foot and Mouth DiseaseRACP Paediatrics

A 4-year-old child presents with a 5-day history of fever, vesicular lesions in the mouth, and a papulovesicular rash on the palms and soles. What is the most likely causative organism?

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Correct answer: E — Coxsackievirus A16 or Enterovirus 71

Hand, foot and mouth disease (HFMD) is caused by enteroviruses, most commonly Coxsackievirus A16 and Enterovirus 71 (EV71). It presents with oral ulcers and a vesicular rash on the palms, soles, and buttocks. EV71 is associated with more severe disease including neurological complications. Management is supportive.

Reference: RCH Melbourne – 2024 – Clinical Practice Guidelines: Hand, Foot and Mouth Disease