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Provoked VTE 3 Months — RACP Adult Medicine MCQ

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EasyHaematologyProvoked VTE 3 MonthsRACP Adult Medicine

A 40-year-old woman developed a provoked DVT after a 14-hour flight while on the OCP. She has no other risk factors, no family history of VTE, and no thrombophilia. She stopped the OCP and has been on rivaroxaban for 3 months. Her DVT has resolved on ultrasound. What is the recommended duration?

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Correct answer: C — 3 months then stop

Provoked DVT (identifiable major transient risk factor: immobility + OCP) — 3 months of anticoagulation is sufficient (ACCP/CHEST 2024). Recurrence risk after stopping is low (~3%/year) when the provoking risk factor is removed. OCP has been ceased (removing the ongoing risk factor). No family history or thrombophilia testing indicated for provoked VTE. Aspirin post-anticoagulation (ASPIRE/WARFASA trials) may modestly reduce recurrence but is not standard practice.

Reference: ESC – 2019 – VTE; CHEST 2024 VTE Duration