UC CRC Surveillance — RACP Adult Medicine MCQ
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Correct answer: A — Consider annual MRI/MRCP or endoscopic ultrasound in an expert trial program
Explanation lettering: D = shown as A · E = shown as B · B = shown as C · A = shown as D · C = shown as E
D is correct. Evidence remains emerging; eviQ supports considering annual MRI/MRCP or EUS from around 50 in BRCA carriers with an affected close relative, preferably within an expert research program. A and B are unproven. C morbidity precludes prophylactic pancreatectomy. E ignores the established pancreatic-risk association.
Reference: eviQ, BRCA1 or BRCA2 risk management (female): https://www.eviq.org.au/cancer-genetics/adult/risk-management/3814-brca1-or-brca2-risk-management-female