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Provoked VTE No Thrombophilia Test — RACP Adult Medicine MCQ

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EasyHaematologyProvoked VTE No Thrombophilia TestRACP Adult Medicine

A 30-year-old woman has a provoked DVT (after long-haul flight with OCP use). She has no family history of VTE. She will stop the OCP. She wants to know if she has a clotting disorder. What is the most appropriate advice regarding thrombophilia testing?

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Correct answer: E — Thrombophilia testing NOT recommended — provoked VTE

Provoked VTE (identifiable transient risk factor: OCP + immobility) does NOT routinely warrant thrombophilia testing. Testing rarely changes management — the VTE was provoked, recurrence risk is low once the provoking factor is removed, and standard 3-month anticoagulation duration is appropriate regardless of thrombophilia status. Thrombophilia testing is considered for: unprovoked VTE, VTE at unusual sites (cerebral, splanchnic), VTE <45 with strong family history, or recurrent VTE.

Reference: BSH – 2024 – Thrombophilia; ASH 2024