Dementia with Lewy Bodies — RACP Adult Medicine MCQ
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Correct answer: B — Dementia with Lewy bodies
Visual hallucinations, fluctuating cognition, RBD, parkinsonism (1-year rule: dementia before or within 1 year of parkinsonism = DLB; parkinsonism >1 year before dementia = PDD), and autonomic dysfunction fulfils revised McKeith criteria for dementia with Lewy bodies. DLB patients are exquisitely sensitive to antipsychotics (can cause severe neuroleptic malignancy/rigidity — AVOID). Cholinesterase inhibitors are first-line for cognitive and neuropsychiatric symptoms.
Reference: McKeith – 2023 – DLB Criteria; eTG Neurology 2024