Severe CAP ICU — RACP Adult Medicine MCQ
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Correct answer: B — ICU admission
CURB-65 ≥4 with septic shock and respiratory failure requiring intubation is severe CAP requiring ICU admission. Empirical IV antibiotics for severe CAP per eTG 2025: ceftriaxone 1 g IV daily PLUS azithromycin 500 mg IV daily (or doxycycline). The combination covers typical (S. pneumoniae, H. influenzae) and atypical (Legionella, Mycoplasma) pathogens. De-escalate based on culture and sensitivity.
Reference: eTG Antibiotic – 2025 – Severe CAP; Surviving Sepsis 2021