Altitude Sickness Prophylaxis — RACP Adult Medicine MCQ

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ModerateRespiratoryAltitude Sickness ProphylaxisRACP Adult Medicine

A 25-year-old man is travelling to Nepal for trekking at high altitude (>3500 m). He has no medical history. He asks about altitude sickness prevention. He will ascend from 2800 m to 5000 m over 5 days. What is the most appropriate pharmacological prophylaxis?

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Correct answer: C — No prophylaxis needed

This question's option set doesn't include the correct drug (acetazolamide). Acetazolamide 125-250 mg BD is the standard pharmacological prophylaxis for acute mountain sickness, started 1 day before ascent. Dexamethasone is an alternative. Non-pharmacological measures are more important: gradual ascent (≤500 m/day above 3000 m), rest days every 1000 m, adequate hydration, and descent if symptomatic. [Note: answer limited by option set]

Reference: eTG – 2024 – Travel Medicine; Wilderness Medical Society 2024