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IE Dental Prophylaxis — RACP Adult Medicine MCQ

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EasyInfectious DiseasesIE Dental ProphylaxisRACP Adult Medicine

A 60-year-old man with a prosthetic mitral valve is undergoing dental extraction. He has no penicillin allergy. What is the most appropriate endocarditis prophylaxis?

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Correct answer: D — Amoxicillin 2 g oral 1 hour before

Prosthetic heart valve is a high-risk cardiac condition for IE. Dental procedures involving manipulation of gingival tissue or periapical region require antibiotic prophylaxis. Amoxicillin 2 g orally 30-60 minutes before the procedure is the standard regimen per eTG and AHA/ESC guidelines. Clindamycin 600 mg oral is the alternative for penicillin allergy.

Reference: eTG Antibiotic – 2025 – IE Prophylaxis; ESC 2023 IE