A 55-year-old woman on sotalol for AF is found to have a QTc of 550 ms on routine ECG. She is asymptomatic. K⁺ is 3.8 mmol/L, Mg²⁺ is 0.8 mmol/L.

Question

A 55-year-old woman on sotalol for AF is found to have a QTc of 550 ms on routine ECG. She is asymptomatic. K⁺ is 3.8 mmol/L, Mg²⁺ is 0.8 mmol/L. What is the most appropriate management?

Accepted Answer

Cease sotalol and switch to an alternative

Answer

Continue sotalol and add mexiletine

Answer

Continue sotalol unchanged

Answer

Add IV magnesium and continue sotalol

Answer

Reduce sotalol dose by 50%

Drug-Induced QT Prolongation — RACP Adult Medicine MCQ

A 55-year-old woman on sotalol for AF is found to have a QTc of 550 ms on routine ECG. She is asymptomatic. K⁺ is 3.8 mmol/L, Mg²⁺ is 0.8 mmol/L. What is the most appropriate management?