Hypokalaemia with Hypomagnesaemia — RACP Adult Medicine MCQ
Instant feedback + full explanation. One question, done properly.
Educational content. Not a substitute for clinical judgement or local policy.
Reveal the answer and explanation
Correct answer: D — IV magnesium sulfate 10 mmol over 1 hour then oral Mg replacement, PLUS IV/oral KCl
Hypokalaemia with concurrent hypomagnesaemia requires magnesium correction FIRST — potassium repletion is ineffective until magnesium is repleted. Magnesium deficiency causes renal potassium wasting via ROMK channels. Give IV MgSO₄ (10-20 mmol over 1-2 hours) followed by oral Mg, PLUS KCl replacement (oral or IV at max 20 mmol/hr peripherally, 40 mmol/hr centrally).
Reference: eTG – 2024 – Electrolyte Replacement; KDIGO 2024