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Type 2 Myocardial Infarction — RACP Adult Medicine MCQ

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HardCardiologyType 2 Myocardial InfarctionRACP Adult Medicine

A patient with septic shock has high-sensitivity troponin 140 ng/L falling to 115 ng/L. There is no chest pain, no ischaemic ECG change and echocardiography shows global rather than regional dysfunction. Which classification is most defensible?

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Correct answer: DAcute non-ischaemic myocardial injury unless objective evidence of myocardial ischaemia emerges

The best answer is “Acute non-ischaemic myocardial injury unless objective evidence of myocardial ischaemia emerges”. A changing troponin concentration supports acute myocardial injury, but myocardial infarction additionally requires clinical, ECG, imaging or angiographic evidence of myocardial ischaemia. Sepsis alone does not establish type 2 infarction, and global rather than regional dysfunction does not define STEMI. A lower second concentration does not make the injury chronic.

Reference: Heart Foundation and CSANZ, Australian acute coronary syndromes guideline 2025: https://www.heartfoundation.org.au/for-professionals/acs-guideline