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CRRT in ICU — RACP Adult Medicine MCQ

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ModerateNephrologyCRRT in ICURACP Adult Medicine

A 70-year-old man with septic shock and AKI (anuria, K⁺ 6.8, pH 7.15, lactate 8 mmol/L) is haemodynamically unstable on noradrenaline. Standard intermittent haemodialysis causes further hypotension. What is the most appropriate dialysis modality?

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Correct answer: AContinuous renal replacement therapy (CRRT)

CRRT (continuous venovenous haemofiltration/haemodialysis) is the preferred modality for AKI in haemodynamically unstable ICU patients. Compared to intermittent HD, CRRT causes less haemodynamic instability (slower fluid and solute removal), maintains more stable electrolytes and acid-base status, and allows concurrent nutritional support. KDIGO 2024 recommends initiating RRT when life-threatening complications exist.

Reference: KDIGO – 2024 – AKI Guidelines; ANZICS 2024