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Iron Poisoning — RACP Adult Medicine MCQ

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ModerateNephrologyIron PoisoningRACP Adult Medicine

A 3-year-old child is brought to ED after ingesting an unknown number of grandmother's iron tablets. Serum iron level is 90 μmol/L (normal <30). He has persistent vomiting and metabolic acidosis. Abdominal X-ray shows radiopaque tablets in the stomach. What is the most appropriate specific antidote?

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Correct answer: ADesferrioxamine

Serum iron >90 μmol/L with GI symptoms and metabolic acidosis indicates severe iron poisoning. Desferrioxamine (IV infusion 15 mg/kg/hr) chelates free iron. Whole bowel irrigation may be used for tablets visible on AXR. Iron poisoning progresses through GI, latent, shock/hepatotoxicity, and stricture phases.

Reference: Toxicology Handbook (Murray) 3rd Ed; eTG – 2024