A 50-year-old woman with SLE presents with fatigue, Hb 78 g/L, reticulocyte count 12%, LDH elevated, haptoglobin undetectable, DAT positive (IgG +

Question

A 50-year-old woman with SLE presents with fatigue, Hb 78 g/L, reticulocyte count 12%, LDH elevated, haptoglobin undetectable, DAT positive (IgG + C3d). She also has thrombocytopenia (platelets 45 × 10⁹/L). What is the most likely haematological complication?

Accepted Answer

Evans syndrome (AIHA + ITP)

Answer

Thrombotic thrombocytopenic purpura

Answer

Myelodysplastic syndrome

Answer

Aplastic anaemia

Answer

Antiphospholipid syndrome

Evans Syndrome in SLE — RACP Adult Medicine MCQ

A 50-year-old woman with SLE presents with fatigue, Hb 78 g/L, reticulocyte count 12%, LDH elevated, haptoglobin undetectable, DAT positive (IgG + C3d). She also has thrombocytopenia (platelets 45 × 10⁹/L). What is the most likely haematological complication?