Sjögren Syndrome — RACP Adult Medicine MCQ
Instant feedback + full explanation. One question, done properly.
Educational content. Not a substitute for clinical judgement or local policy.
Reveal the answer and explanation
Correct answer: C — Arrange urgent expert assessment and tissue diagnosis for possible lymphoma
The best answer is “Arrange urgent expert assessment and tissue diagnosis for possible lymphoma”. Sjögren syndrome increases B-cell lymphoma risk; persistent asymmetric salivary enlargement, systemic symptoms, purpura and hypocomplementaemia are red flags. Imaging and appropriately targeted biopsy should precede empiric immunosuppression when feasible because treatment can obscure histology. Symptomatic sicca care does not address a possible malignancy.
Reference: Australian Rheumatology Association: Sjogren syndrome: https://rheumatology.org.au/For-Patients/Adult-Medication-Information