skip to main content

Acute Hepatitis A — RACP Adult Medicine MCQ

Instant feedback + full explanation. One question, done properly.

EasyGastroenterologyAcute Hepatitis ARACP Adult Medicine

A 25-year-old woman presents with malaise and jaundice. LFTs: Bilirubin 95 μmol/L (conjugated 70 μmol/L), ALP 120 U/L, GGT 55 U/L, ALT 2800 U/L, AST 3200 U/L. INR 1.8. Hepatitis A IgM is positive. What is the most likely LFT pattern?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Hepatocellular injury

Markedly elevated transaminases (ALT and AST >10× ULN) with relatively normal ALP characterises hepatocellular injury. The R-factor (ALT/ALP, using ULN multiples) >5 confirms hepatocellular pattern. Positive hepatitis A IgM confirms acute hepatitis A. The elevated INR indicates impaired synthetic function, requiring monitoring for acute liver failure.

Reference: eTG Gastrointestinal – 2024 – Acute Hepatitis