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Anti-Synthetase Syndrome — RACP Adult Medicine MCQ

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HardRheumatologyAnti-Synthetase SyndromeRACP Adult Medicine

During peripheral doxorubicin infusion, a patient develops burning pain, swelling and absent blood return around the cannula. What is the first management sequence?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: DStop infusion, aspirate through cannula and activate the extravasation protocol

Explanation lettering: C = shown as A · E = shown as B · B = shown as C · A = shown as E

D is correct. Suspected vesicant extravasation requires immediate stop, aspiration through the retained device and drug-specific management including cold localisation and antidote consideration. E removes access for aspiration and spreads drug. A flushes vesicant into tissue. B increases injury. C delays treatment and conceals progression.

Reference: eviQ, Extravasation management clinical procedure: https://www.eviq.org.au/clinical-resources/extravasation/4156-extravasation-management-clinical-procedure