Diffuse Systemic Sclerosis — RACP Adult Medicine MCQ
Instant feedback + full explanation. One question, done properly.
Educational content. Not a substitute for clinical judgement or local policy.
Reveal the answer and explanation
Correct answer: B — Urgently investigate for Sjögren-associated B-cell lymphoma with tissue diagnosis
Explanation lettering: C = shown as B · E = shown as C · B = shown as D · D = shown as E
C is correct. Persistent asymmetric gland enlargement plus constitutional symptoms, purpura, cryoglobulinaemia and low complement are lymphoma red flags requiring urgent imaging and biopsy planning. D delays diagnosis. E cannot explain systemic features. A assumes infection without supportive signs. B ignores a systemic lymphoproliferative phenotype.
Reference: Australian Rheumatology Association, Sjogren disease: https://rheumatology.org.au/For-Patients/Adult-Medication-Information/Sjogrens-Syndrome