Irritation Fibroma Diagnosis — NDEB AFK MCQ

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EasyOral PathologyIrritation Fibroma DiagnosisNDEB AFK

A patient presents with a smooth, pink, dome-shaped, firm, sessile nodule on the buccal mucosa along the occlusal line. It has been present for months without change. What is the most likely diagnosis?

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Correct answer: C — Fibroma (irritation fibroma/focal fibrous hyperplasia)

An irritation fibroma (focal fibrous hyperplasia) is the most common benign 'tumour' of the oral cavity — it is actually a reactive hyperplasia rather than a true neoplasm. It presents as a smooth, pink, dome-shaped, firm, painless, sessile or pedunculated nodule, most commonly on the buccal mucosa along the bite line, lateral tongue, or lower lip. It results from chronic irritation (biting, trauma). Treatment is conservative excision with minimal recurrence. Histologically, it consists of dense fibrous connective tissue with few blood vessels and overlying stratified squamous epithelium.

Reference: Neville – Oral and Maxillofacial Pathology, 4th ed., 2016