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Ehlers-Danlos Dental Manifestations — NDEB AFK MCQ

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HardPeriodontologyEhlers-Danlos Dental ManifestationsNDEB AFK

Which hereditary condition affecting connective tissue is associated with hypermobility of the TMJ, joint subluxation, easy bruising, and periodontal breakdown?

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Correct answer: AEhlers-Danlos syndrome

Ehlers-Danlos syndrome (EDS) is a group of inherited connective tissue disorders characterised by defects in collagen synthesis or structure. Dental and oral manifestations include: TMJ hypermobility and subluxation/dislocation, gingival fragility and bleeding, early-onset periodontitis (particularly EDS type VIII/periodontal type), easy bruising, poor wound healing, and mitral valve prolapse. The joint hypermobility can cause TMJ dislocation during dental procedures (maintain jaw support during treatment). EDS type VIII specifically features severe periodontal destruction with premature tooth loss.

Reference: Neville – Oral and Maxillofacial Pathology, 4th ed., 2016