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Bell Stage Histodifferentiation — NDEB AFK MCQ

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ModerateBiomedical SciencesBell Stage HistodifferentiationNDEB AFK

Which developmental stage of the tooth germ is characterised by the differentiation of the four distinct layers: inner enamel epithelium, stratum intermedium, stellate reticulum, and outer enamel epithelium?

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Correct answer: E — Bell stage

The bell stage of tooth development is characterised by histodifferentiation — the enamel organ differentiates into four distinct layers: (1) inner enamel epithelium (IEE) — will become ameloblasts; (2) stratum intermedium — supports ameloblast function; (3) stellate reticulum — cushioning/nutritive layer; (4) outer enamel epithelium (OEE) — protective layer. The dental papilla (future dentin and pulp) and dental follicle (future periodontium) are also well defined. The cervical loop (junction of IEE and OEE) will become Hertwig epithelial root sheath.

Reference: Nanci – Ten Cate's Oral Histology, 9th ed., 2017