Naloxone in Emergency Kit — NDEB AFK MCQ

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EasyMedical Emergencies in DentistryNaloxone in Emergency KitNDEB AFK

Which drug should always be available in a dental office emergency kit for the reversal of opioid-induced respiratory depression?

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Correct answer: B — Naloxone

Naloxone (0.4-2 mg IV/IM/SC) should be available in all dental offices that administer or prescribe opioids, or that provide sedation. It is a competitive opioid receptor antagonist that rapidly reverses opioid-induced respiratory depression, sedation, and hypotension. Its half-life (30-90 min) is shorter than most opioids, so re-sedation can occur. It is also available as an intranasal spray (Narcan Nasal Spray). All Canadian dental regulatory authorities recommend emergency drug kits include naloxone.

Reference: Malamed – Medical Emergencies in the Dental Office, 8th ed., 2022