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PCD Target Lesion — NDEB AFK MCQ

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ModerateOral PathologyPCD Target LesionNDEB AFK

A 30-year-old female presents with a slowly enlarging firm swelling in the anterior mandibular region. Radiograph shows a well-defined mixed radiolucent-radiopaque lesion with concentric radiopaque rings ('driven snow' or 'target lesion' appearance). What is the most likely diagnosis?

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Correct answer: E — Periapical cemental dysplasia (intermediate stage)

A mixed radiolucent-radiopaque lesion in the anterior mandible of a middle-aged woman with vital teeth and a target-like appearance (central radiopacity surrounded by a radiolucent halo) is characteristic of periapical cemental dysplasia (PCD) in its intermediate (cementoblastic) stage. The early stage mimics periapical pathology (radiolucency). The intermediate stage shows mixed density. The mature stage is predominantly radiopaque. The teeth are vital — no treatment is needed. Biopsy is contraindicated.

Reference: Neville – Oral and Maxillofacial Pathology, 4th ed., 2016