Biocompatibility Definition — NDEB AFK MCQ
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Correct answer: C — The ability of a material to perform with an appropriate host response in a specific application
Biocompatibility (as defined by Williams, 1987) is the ability of a material to perform with an appropriate host response in a specific application. This means the material does not cause adverse local or systemic effects (toxicity, immunogenicity, mutagenicity, carcinogenicity) while fulfilling its intended clinical function. No material is completely inert — all materials interact with biological tissues to some degree. The appropriateness of the host response depends on the application (e.g., acceptable for a transient material may differ from a permanent implant).
Reference: Anusavice – Phillips' Science of Dental Materials, 13th ed., 2022