IE Prophylaxis Dose — NDEB AFK MCQ
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Correct answer: E — 2 g
The standard adult dose for IE prophylaxis is amoxicillin 2 g PO, administered 30-60 minutes before the dental procedure. For children, the dose is 50 mg/kg PO (maximum 2 g). This single pre-procedural dose provides adequate blood levels to cover the period of transient bacteraemia induced by the dental procedure. No post-procedural dose is required. For patients unable to take oral medication, ampicillin 2 g IM or IV is the alternative.
Reference: AHA – Prevention of Infective Endocarditis Guidelines, 2021; CDA Position Statement