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Erythema Multiforme — NDEB AFK MCQ

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ModerateOral MedicineErythema MultiformeNDEB AFK

Which of the following conditions presents with target (iris) lesions on the skin and erosive oral lesions?

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Correct answer: DErythema multiforme

Erythema multiforme (EM) is an acute, self-limiting immune-mediated condition characterised by target (iris/bull's eye) lesions on the skin (concentric rings of colour change) and/or erosive, crusted, haemorrhagic oral lesions (particularly the lips). EM minor primarily affects skin; EM major affects skin and mucous membranes. The most common trigger is herpes simplex virus (HSV) infection. Stevens-Johnson syndrome and toxic epidermal necrolysis are severe forms. Oral involvement causes painful erosions with haemorrhagic crusting of the lips.

Reference: Neville – Oral and Maxillofacial Pathology, 4th ed., 2016